@Kikaah et @flip ça n'existe pas encore ...
Une étude en cours en france ...
https://dog-genetics.genouest.org/dysplasie-de-la-hanche/
En 2019 , un avancement mais à confirmer avec d'autre études :
https://www.vetitude.fr/dysplasie-canine-de-la-hanche-identification-de-genes-impliques/
L'étude elle même :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935090/
In conclusion, we have performed a successful association study with a large cohort of accurately and robustly phenotyped German Shepherds and describe three loci with genome-wide significance and two suggestive loci for CHD-related traits. The candidate genes include NOX3 and ARID1B on chromosome 1, NOG on chromosome 9, and NANOS1 on chromosome 28. ------Future studies will focus on ascertaining their role in CHD by resequencing the candidate region for putative risk variants.-----
Un test a été développé mais invalidé
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542656/
Enfin une autre étude publiée en janvier 2021 est sortie mais non, toujours pas de test puisque chaque étude se rapproche du but , mais aussi conclue qu'il faut une autre étude plus poussée afin d'identifier clairements les locus responsables de la dysplasie
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-021-07375-*
Dernière publication d'étude en date septembre 2021
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-021-07945-z
"Despite the efforts from various breeding programs, CHD remains a common disease in dogs with a large impact on animal welfare, but the biological basis is not well-understood. In this study, we confirmed the complex genetic nature of the trait, with multiple loci associated with CHD in German Shepherd dogs and also observed that most associated SNPs are population-specific. However, some genomic regions were only identified in the meta-analysis of three populations, thus indicating that routinely assessed CHD information collected across countries provides an opportunity to increase sample sizes and statistical power for association studies. The lack of standardisation of CHD assessment schemes poses a challenge, but conversion of traits can be utilised to overcome this obstacle. ------Further investigation into the population-specific nature of CHD will help to uncover the biological basis of this disease and will inform selection schemes.------"